Onglyza

When DPP-4 inhibitor drugs like Onglyza first entered the market, they were “touted as the ‘new darlings of diabetes treatment’ – the biggest breakthrough since the discovery of insulin nearly a hundred years before,” according to British Medical Journal editor Deborah Cohen. However, mounting evidence has linked Onglyza and other DPP-4 inhibitor drugs to an increased risk of potentially life-threatening side effects, including pancreatitis, pancreatic cancer, and heart failure.

If you have been diagnosed with congestive heart failure, heart failure or cardiac failure, and used type 2 diabetes drugs Onglyza or Kombiglyze, you are likely eligible to file a claim for compensation against the manufacturer of these drugs. With a qualified Onglyza Hearth Failure Compensation Attorney on your side, you can protect your legal rights and seek fair and timely reimbursement for your losses.

Potential Side Effects Associated with Onglyza

Onglyza (saxagliptin) is a incretin mimetic that was approved by the U.S. Food and Drug Administration (FDA) in 2009, and is commonly prescribed, along with diet and exercise, to help control high blood sugar in patients with Type 2 diabetes who do not suffer from a condition called diabetic ketoacidosis. Onglyza belongs to a class of diabetes drugs known as DPP-4 inhibitors, which are designed to help the pancreas secrete more insulin and prevent the liver from making excess sugar. However, serious concerns have been raised recently about the potential for Onglyza to cause an increased risk of:

Studies Linking Onglyza to Injuries

Some of the most serious side effects tied to Onglyza treatment are increased risk of Congestive Heart Failure or Cardiac Failure. Pancreatic Cancer Lawsuit, a potentially life-threatening cancer that is often not diagnosed until the later stages, has been linked to use of similar drugs, Januvia, Victoza, Byetta and Janumet. The FDA has issued warnings regarding the potential risk of pancreatitis and pancreatic cancer associated with diabetes drugs similar to Onglyza, and one study published in the March 2013 issue of the medical journal Diabetes linked DPP-4 inhibitor drugs like Onglyza to an increased risk of abnormal pre-cancerous cells in the autopsied pancreases of people taking the medications.

According to the study, DPP-4 inhibitor drugs are designed to increase the size and number of beta cells in the pancreas, which are responsible for secreting insulin. The researchers involved in the study found that, while the diabetes medications did indeed increase the number of beta cells, the cells were abnormal, and were accompanied by small tumors called adenomas, which can become malignant. More importantly, the researchers reported that this change took place only in Type 2 diabetes patients who took DPP-4 drugs like Onglyza or GLP-1 drugs, and not in diabetes patients taking other medications.

Another side effect potentially linked to Onglyza treatment is heart failure, and in April 2015, an FDA panel recommended that the Onglyza drug label be updated to include an increased risk of heart failure among patients using the diabetes medication. This recommendation came after data from a study involving 16,000 patients indicated that those who took Onglyza faced a 27% higher risk of hospitalization due to heart failure, compared to those who didn’t take the medication. Based on these findings, Dr. Anthony DeMaria, editor in chief of the Journal of the American College of Cardiology, advised patients at risk for heart failure to avoid taking Onglyza.

A Qualified Onglyza Attorney Can Help

Hundreds of patients who used incretin-based therapies like Onglyza in the past have filed claims against the drug manufacturing companies, after suffering pancreatitis, pancreatic cancer, or another major complication. All of the product liability claims involve similar allegations that the drug makers failed to provide adequate warnings to consumers and doctors about the risk of side effects from the popular diabetes drugs.

If you took Onglyza in the past, and you have since suffered side effects like pancreatitis, pancreatic cancer, or heart failure, contact a reputable Onglyza attorney today for legal help. You may have grounds to file an Onglyza lawsuit against AstraZeneca and Bristol-Myers Squibb, in order to pursue financial compensation for your injuries and medical bills.

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